ABSCIEX与美CDC合作改善临床研究

共同努力使LC/MS在临床实验室对于类固醇激素测试更加便利

　　福斯特市，加利福尼亚，AB SCIEX，生命科学分析技术的全球领导者，近日宣布与美疾病控制与预防中心（CDC）合作，并创立CDC基金会来支持质谱技术在临床实验室中激素检测的运用。这一合作的目的在于帮助支持CDC的激素标准化项目，从而提高实验室结果的可靠性，帮助评估疾病风险并监控治疗。

　　建立激素标准化项目的目标是应对临床研究中现阶段面临的挑战，这些挑战包括：在研究和测量系统中缺少数据的可比性；缺乏尤其是在低浓度范围内缺乏适当的检测性能，比如在妇女和儿童体内观测到的睾丸激素级。为了推进这一项目，CDC正在开发一个参考方法，该方法用质谱来提高结果的可比性、特异性和可靠性，并帮助实现更加准确的测试。

　　质谱是一种先进的科学仪器，基于分子组成的不同来分析化合物。质谱能够扫描、鉴定和定量测定各种分子，包括扩睾丸激素和其它激素。CDC的参考方法使用的是液相色谱-质谱联用方法（LC/MS）。AB SCIEX通过贡献CDC基金的方式向CDC提供了AB SCIEX QTRAP^® 5500系统。QTRAP系统是获奖的质谱产品，是整体解决方案中的一部分，整体解决方案还包括用于临床研究的“可立快”（Cliquid^®） 软件，这是一款自动化的应用软件，用于简化质谱在临床研究中的流程。

AB SCIEX QTRAP 5500质谱仪

可立快Cliquid软件

　　本网站收录相关仪器：

　　QTRAP5500 四极杆-线性阱杂交质谱仪

　　Joe Anacleto, AB SCIEX公司副总裁兼应用市场和临床研究事业部经理说：“AB SCIEX尽其所能地通过扩展质谱的应用来帮助提升临床研究的水平。我们十分珍惜这次与CDC合作的机会，帮助CDC不断提高激素测定结果的准确性。AB SCIEX临床研究解决方案为这一重要分析提供了一流的领先技术。”

　　关于AB SCIEX

　　AB SCIEX是生命科学分析技术开发领域的全球领先企业，帮助科学家应对复杂的科学挑战。公司提供科学仪器、软件和服务，用于发现新药、促进医学科学发展、保护食品供应链和环境。AB SCIEX的技术解决方案结合了最高的性能和最高的稳定性，确保我们的用户进行科学发现、可靠地传递结果和提高生命质量。AB SCIEX拥有近30年的创新历史，在市场中一直出于领先地位，其前身为美国应用生物系统公司（Applied Biosystems）和美迪希（MDS）实验仪器公司的合资企业。2010年1月30 日，AB SCIEX作为丹纳赫集团的子公司开始运营。更多资料请访问官网：www.absciex.com。

　　参考英文：

AB SCIEX Collaborates with the Centers for Disease Control and Prevention to Improve Clinical Research

　　Joint efforts to facilitate the use of LC/MS in clinical laboratories for steroid hormone testing

　　FOSTER CITY, Calif. – AB SCIEX, a global leader in life science analytical technologies, announced a collaboration with the Centers for Disease Control and Prevention (CDC) and the CDC Foundation to facilitate the use of mass spectrometry technologies in clinical laboratories for hormone testing. This collaboration is intended to help support the CDC's Hormone Standardization Project for improving the reliability of laboratory results used to help assess disease risk and monitor treatment.

　　The Hormone Standardization Project aims to address current challenges in clinical research, including lack of comparability of data across studies and measurement systems as well as lack of appropriate performance of assays, especially at low concentrations, such as testosterone levels observed in women and children. To advance this project, the CDC is working to develop a reference method using mass spectrometry to improve comparability, specificity, and reliability of results and help facilitate more accurate testing practices.

　　Mass spectrometry is an advanced scientific technique used to analyze compounds based on their molecular composition. Mass spectrometers scan, identify, and measure the quantity of various molecules, including testosterone and other hormones. The CDC's reference method utilizes mass spectrometry combined with high-performance liquid chromatography (LC/MS). AB SCIEX provided the CDC with the use of an AB SCIEX QTRAP® 5500 System through a contribution to the CDC Foundation. The QTRAP system is an award-winning mass spectrometer that is part of an integrated solution, which also features Cliquid® Software for Clinical Research, an automated software application designed to simplify the use of mass spectrometry for clinical researchers.

　　Joe Anacleto, Vice President and General Manager of the Applied Markets and Clinical Research Business, AB SCIEX

　　 “AB SCIEX is well-positioned to help advance clinical research through the expanded use of mass spectrometry. We value the opportunity to assist the CDC in advancing improved accuracy of results for hormone testing. AB SCIEX clinical research solutions use best-in-class technology for this critical analysis.”

　　About AB SCIEX

　　AB SCIEX is a global leader in the development of life science analytical technologies that help answer complex scientific challenges. The company provides scientific instrumentation, software and services used to discover new drugs, advance medical science and protect the food supply and the environment. AB SCIEX technology solutions combine the highest performance with the highest reliability to enable our customers to fuel scientific discovery, deliver results with confidence and improve the quality of life. The company has a more than 20-year history of innovation and market leadership as the former Applied Biosystems/MDS Analytical Technologies joint venture. For more information about AB SCIEX, go to www.absciex.com. Follow AB SCIEX on Twitter @ABSCIEX and on Facebook.

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　　AB SCIEX, mass spectrometry, CDC, testosterone, hormone testing, QTRAP, clinical research, Hormone Standardization Project