发布时间:2022-08-16 07:42 原文链接: KITLG基因编码功能及结构描述

该基因编码KIT位点编码的酪氨酸激酶受体配体这种配体是一种多效性因子,在子宫生殖细胞、神经细胞发育和造血中起作用,所有这些都被认为反映了细胞迁移的作用在成人中,它的功能是多方面的,而主要是以它在造血方面的持续需求而闻名。已经发现了两个编码不同亚型的转录变体。[由RefSeq提供,2008年7月]

This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]