该基因编码Rho-GTPase激活蛋白超家族的一个成员编码蛋白可能作为Rho-GTPase激活蛋白发挥作用这种基因的改变可能与多种疾病有关，包括类风湿性关节炎、腹腔疾病和多发性硬化症。交替剪接导致编码不同亚型的多个转录变体。
This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms.