该基因是TIS11早期反应基因家族的成员家族成员是由不同的激动剂如佛波酯tpa和多肽丝裂原egf诱导的。编码蛋白包含一个具有重复cys-his基序的锌指区。这种假定的核转录因子很可能在调节对生长因子的反应中发挥作用。
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.