《自然》2008年度最佳论文（22篇pdf）

《自然》评出2008年度最佳论文

英国《自然》杂志近日评出了其2008年度发表的最佳论文，共22篇，覆盖了生命科学、物理学、化学、天文学、医学、海洋学等

多个领域。

1. 哪里去找磁单极子

相关论文：Magnetic monopoles in spin ice

2. 以DNA为基础的纳米结构

相关论文：Programming biomolecular self-assembly pathways

DNA-guided crystallization of colloidal nanoparticles

DNA-programmable nanoparticle crystallization

3. 遗失的反物质

相关论文：Difference in direct charge-parity violation between charged and neutral B meson decays

4. 人工酶

相关论文：Kemp elimination catalysts by computational enzyme design

5. 来自远古的大气

相关论文：High-resolution carbon dioxide concentration record 650,000–800,000 years before present

Orbital and millennial-scale features of atmospheric CH4 over the past 800,000 years

6. 温度下降的那一天

相关论文：A large discontinuity in the mid-twentieth century in observed global-mean surface temperature

7. 带颜色的组织

相关论文：Micro-engineered local field control for high-sensitivity multispectral MRI

8. 令人吃惊的脂肪细胞

相关论文：PRDM16 controls a brown fat/skeletal muscle switch

9. 海洋生物学的剧变

相关论文：Major viral impact on the functioning of benthic deep-sea ecosystems

10. 目睹黑洞

相关论文：Event-horizon-scale structure in the supermassive black hole candidate at the Galactic Centre

11. 人造树

相关论文：The transpiration of water at negative pressures in a synthetic tree

12. 重访细胞生物学

相关论文：Frequency-modulated nuclear localization bursts coordinate gene regulation

13. 观看物种形成

相关论文：Speciation through sensory drive in cichlid fish

14. 诱导糖尿病小鼠产生胰岛素

相关论文：In vivo reprogramming of adult pancreatic exocrine cells toβ–cells

15. 跨越细胞膜

相关论文：Structure of a complex of the ATPase SecA and the protein-translocation channel

16，基因组测序

相关论文：Accurate whole human genome sequencing using reversible terminator chemistry

The diploid genome sequence of an Asian individual

17. 癌症干细胞假说

相关论文：Efficient tumour formation by single human melanoma cells

18. 神经运动弥补术

相关论文：Direct control of paralysed muscles by cortical