该基因编码一种参与花生四烯酸转化为12R-羟基二十碳四烯酸的酶。该基因突变与非大疱性先天性鱼鳞病样红皮病有关。[由RefSeq提供，2015年9月]
This gene encodes an enzyme involved in the conversion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma. [provided by RefSeq, Sep 2015]