Cerno和安捷伦共同开发MassWorks在GC／MSD上的应用

Cerno Bioscience和安捷伦共同开发MassWorks在GC/MSD上的应用

MassWorks校正软件使单四极杆仪器可以方便地鉴定未知物

DANBURY, Conn., and SANTA CLARA, Calif., , 11/3/2009  --

      Cerno Bioscience和安捷伦科技（NYSE:A）今天宣布，双方将共同开发Cerno公司的MassWorks软件在安捷伦GC/MSD气质联用仪上的应用。这种新型的校正软件提高了安捷伦单级四极杆气质联用仪（GC/MSD）的质量准确度，从而可以鉴定未知化合物。而实现上述功能，以前通常要求使用比GC/MSD昂贵得多的、更大的仪器，比如四极杆-飞行时间串联质谱（Q-TOF），或傅里叶变换离子回旋共振质谱（FT ICR MS）。

      用于GC/MSD的MassWorks软件，使用Cerno公司ZL的技术，使用峰形校正工具校正安捷伦GC/MSD的原始数据，然后使用建立在谱图准确度基础上的CLIPS分子式识别工具。这种技术显著地提高了质量准确度，使单级四极杆质谱能够鉴定未知化合物。除了可以在不使用任何谱库的情况下鉴定化合物，分子式识别工具也可在谱库检索时提高速度、增加确定性。这种合并了安捷伦GC/MSD化学工作站和Cerno的MassWorks的能力，意味着现在用户可以获得一种经济的、可以替代高分辨GC/MS系统的解决方案用于分子式鉴定。

      “合并安捷伦的GC/MS和Cerno的MassWorks，为最终用户提供真正的价值组合。” 安捷伦副总裁和质谱部总经理Chris Toney说，“考虑到相关的花费和延误，客户现在可以使用他们实验室的主力单四极杆质谱来鉴定未知物，而不必依赖更专一的高分辨率质谱。”

      “我们非常高兴能和安捷伦公司建立合作关系，安捷伦是GC/MS公认的市场领先者。安捷伦具有很大的安装基础，客户遍及全球，更多客户将能够接触到MassWorks，” Cerno Bioscience公司的创立者和总裁王永东说，“通过为GC/MS市场的客户专门配置和定价，我们将使针对GC/MS的解决方案对所有的GC/MS实验室来说，更具有吸引力。”

       MassWorks兼容于安捷伦公司的5975和5973 GC/MS气质联用仪，可运行在安捷伦MSD化学工作站上。关于对更旧的系统是否兼容，请联系Cerno或安捷伦公司。

Cerno Bioscience, Agilent Technologies to Co-Market MassWorks for GC/MSD 
 
Calibration Software Enables Single Quadrupole Instruments to Easily Identify Unknowns 

 
DANBURY, Conn., and SANTA CLARA, Calif., , 11/3/2009  --
 
Cerno Bioscience and Agilent Technologies Inc. (NYSE: A) today announced they will jointly market Cerno's MassWorks calibration software to Agilent GC/MSD ChemStation users. This novel calibration increases the mass accuracy of Agilent's single quadrupole GC/MSD sufficiently to identify unknown compounds. This normally requires use of much more expensive, larger instruments such as Quadrupole Time-of-Flight, or Fourier Transform Ion Resonance mass spectrometers.

MassWorks for GC/MSD uses Cerno's patented technology to calibrate raw MS data from Agilent's GC/MSD using peak shape, followed by CLIP formula ID based on spectral accuracy. This technique dramatically improves mass accuracy and enables single-quad instruments to identify unknown compounds. In addition to enabling compound identification without a library, the formula ID function also speeds and adds confidence to library searches. The combined capabilities of the Agilent GC/MSD Chemstation and Cerno's MassWorks means there is now an economic alternative to high-resolution GC/MS systems for formula ID.

"The combination of Agilent's GC/MS with Cerno's MassWorks holds real value for end users," said Chris Toney, Agilent vice president and general manager, Mass Spec Systems. "Customers can use their workhorse single-quad instruments to identify unknowns rather than rely on more specialized instruments with associated costs and delays."

"We're delighted to enter into this relationship with Agilent, a recognized market leader in GC/MS. With Agilent's large install base and worldwide reach, we will be able to make MassWorks available to many more users," said Dr. Yongdong Wang, founder and president of Cerno Bioscience. "By configuring and pricing MassWorks specifically for the GC/MS market, we can make this solution more attractive for all GC/MS laboratories."

MassWorks is compatible with Agilent 5975 and 5973 GC/MS instruments running Agilent MSD ChemStation software. To determine compatibility with older systems, please contact Cerno or Agilent.