发布时间:2022-08-16 14:49 原文链接: NONO基因编码功能及结构描述

该基因编码一种rna结合蛋白,在细胞核中起着多种作用,包括转录调控和rna剪接。在乳头状肾细胞癌中观察到该基因与转录因子e3基因的重排。另外,已经描述了剪接转录变体。假基因存在于染色体2和16上。

This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. [provided by RefSeq, Feb 2009]