发布时间:2022-08-22 16:36 原文链接: SOX1基因编码的功能和结构描述

这个无内含子的基因编码一个SOX(SRY相关HMG-box)转录因子家族的成员,该家族参与胚胎发育的调控和细胞命运的决定编码的蛋白质在与其他蛋白质形成蛋白质复合物后可作为转录激活剂在小鼠中,一种类似的蛋白质调节γ-晶体蛋白基因,对晶状体发育至关重要。

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.