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BCellReceptor信号通路图

B cells produce immunoglobulins (Ig, antibodies) that specifically bind antigen molecules. B cells first produce a membrane-bound form of immunoglobulin, the B cell receptor, as part of B cell differentiation. Each B cell expresses one immunoglobulin but the population of B cells in each individual display a wide variety of antigen specificity, with each cell expressing Ig on its surface as part of the B ce......阅读全文

T Cell Receptor 信号通路图

The  T Cell Receptor plays a key role in the immune system. The specificity  of the receptor is governed by the binding site formed from the mature  a

B Cell Receptor 信号通路图

B cells produce immunoglobulins (Ig, antibodies) that specifically bind antigen molecules. B cells first produce a membrane-bound form of immunogl

B Cell Receptor Complex

B cells produce immunoglobulins (Ig, antibodies) that specifically bind antigen molecules. B cells first produce a membrane-b

T Cell Receptor Signaling Pathway

The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is governed by the binding site formed from the mature alph

T Cell Receptor and CD3 Complex

The T cell receptor is a cell-surface receptor that recognizes specific antigen to stimulate the T cell response to that antigen. The T cell receptor

IL-2 Receptor Beta Chain in T cell Activation

The IL-2 receptor is a key component of immune signaling and is required for the activation, proliferation, and survival of T cells. This receptor is

青年哈佛教授《Cell》解析抑癌信号通路

  越来越多的研究表明,细胞可以通过操控其信号分子的某个时间段的行为,也就是动态行为,发送并接受信息。近期来自哈佛医学院的研究人员以此为焦点,介绍了信号动态编码和解码信号信息的研究进程,并指出信号分子动态作用机制传递细胞信息,未来也许能用于疾病的治疗。这一综述发表于Cell杂志上。   这一综述由

Cell:中美学者揭示神经与肠道信号通路

  大脑是身体的指挥中心,支配着人类的生命活动。但其实,人体里还存在着一个“第二大脑”,那就是肠道。  肠道可不仅仅是一个精巧的消化系统,已有的科学研究表明,神经细胞与肠道之间可以相互作用,但它们之间具体如何相互作用,信号如何从一个组织传递到另一个组织,并系统调控机体整体的代谢水平和衰老进程,一直是

Sonic Hedgehog (SHH) Receptor Ptc1 Regulates cell cycle

Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental factor. Shh provides a morphogenic signal in the devel

Cell:Hedgehog信号通路为何引发乳腺癌转移?

  长链非编码RNA(lncRNAs)与乳腺癌有牵连,但其在癌症转移和肿瘤生长中的相关机制仍不甚明朗。  得克萨斯大学MD安德森癌症中心科学家报告说,刺猬(hedgehog)是一个独特的细胞信号转导通路(其已知能导致许多类型的癌症),亦可能是乳腺癌转移的背后机制。这种分子与BCAR4协同,给肿瘤生长