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KeratinocyteDifferentiation

The epidermis, which provides a protective barrier that undergoes a constant renewal, is a multi-layered tissue with the proliferating cells located in the basal layer. As cells leave the basal layer the underog significant differentiation, biochemical and morphological remodeling. The final differentiation results in the formation of corneocytes. In vitro keratinocytes mimic this process. Several genes mark keratino......阅读全文

Effects of calcineurin in Keratinocyte Differentiation

The differentiation of keratinocytes constantly replenishes the upper layers of human skin we lose each day. One factor that contributes to terminal k

中国农大PLOS解析脱发分子机制

  今年三月份,中国农业大学生物学院农业生物技术国家重点实验室的于政权博士,与美国宾夕法尼亚大学的研究人员合作,发现了结肠癌的一个新元凶——一种称为 MSI2的蛋白质。他们的研究结果,为结直肠癌的干预治疗提供了新靶点,并增强了我们对于癌症发生、发展复杂性的认识。这项结果发表在国际知名期刊《Natur

Heterogeneity of Single-Cell Gene Expression Across Phenotypically(二)

 Figure 2: Verification of C1 Single-Cell mRNA-Seq data quality. a)ERCC  RNA Spike-In Control Mix 1 was applied to a C1 IFC at a total &nbs

Role of nicotinic acetylcholine receptors in the regulation of apoptosis

Nicotinic acetylcholine receptors are essential for neuromuscular signaling and are also expressed in non-neuronal tissues, where their function is le