会议主题:Antibody Discovering
主办单位:SLAS, SIAIS(上海科技大学免疫化学研究所)
会议时间时间:2014年10月23日12:15-16:00
会议地点:上海张江海科路100号行政楼一楼礼堂
注册费用:免费 (Shuttle Bus and Lunch Provided** please see the bottom of the page)
报名链接:http://asia-slas.org/registration.aspx?info_lb=25&flag=4&id=129
报名邮箱: asia@slas.org 注明报名参加六月上海研讨会,姓名、电话、手机、公司、职位等联系方式。
电话报名:021-2312 3644
赞助联系: kyang@slas.org 021-2312 3644
日程安排:
12:15-13:15 Lunch Session
13:30-13:40 Main Session Introduction
13:40-14:20 Cell Based Hybridoma Screening for Therapeutic Antibody Discovery
This talk will be based on an internal case study project in his company and share with colleagues in academia or industry our experiences with cell based hybridoma screening.
Duan Qing, Principal Scientist, Biologics, Shanghai Chempartner
Dr. Duan has the extensive experience in drug discovery for both small molecular cmpds and therapeutic antibodies. Strong record of productivity in deleverying multiple drug candidates for downstream development. He got the Ph.D. from Institute of Health Science, Shanghai Institutes for Biological Science, Chinese Academy of Sciences.
14:20-15:00 Innovation and Modern Medicine: Discovering Novel Biotherapeutics
Since its birth 40 years ago, biotherapeutics have changed from simple recombinant proteins to engineered therapeutic proteins and antibodies, and to cell therapy and gene therapy. In fact, biotherapeutics have become an important component of modern medicine. The technology advancement for genetic engineering made it possible to create safe and efficacious biological drugs used to treat disease such as rheumatoid arthritis, multiple sclerosis, bone degeneration and cancer. This presentation will review the evolving biotherapeutic modalities and the technologies used for their generation.
Zhijian Lu, Head of Biologics Discovery Unit, Novartis Shanghai
Dr. Zhijian Lu has a Bachelor’s degree in chemistry from Jilin University, China, and a PhD degree from Boston University. He did his post-doctoral studies in Dr. Gobind Khorana’s lab in MIT on structure-function relationship of rhodopsin. Dr. Lu started working in Genetics Institute/Wyeth/Pfizer 20 years ago, where his researches were in the areas of cytokine structure/function studies, signal transduction/functional proteomics, and the discovery of biotherapeutics including recombinant proteins and monoclonal antibodies. He joint Novartis in 2011 as the head of Novartis biologics discovery unit in Shanghai.
15:00-15:20 Coffee Break
15:20-16:00 Combinatorial Antibody Library, Theory & Applications
Combinatorial antibody libraries have changed the face of immunochemistry because they allow construction of an immune system in a test tube. The diversity of such systems it a least three In orders of magnitude larger than the natural repertoire. The key to the selection process has been the linkage between recognition and replication in phage, yeast, or bacterial systems. Recently, such libraries have been incorporated into lentiviruses for phenotypic selections. Such selections are most powerful when they are autocrine based. In this talk, Dr. Yang will present results that demonstrate the power of this approach.
Guang Yang, Deputy Director, Shanghai Institute for Advanced Immunochemical Studies, Shanghai Tech University
Dr. Guang Yang finished his Ph.D. education at College Park, University of Maryland in 1995. Recently he won the Talent Award of Innovation and Entrepreneur of Jiangsu Province in 2012. His research focus include phenotypic assay development and application; examination and characterization of therapeutic antibodies and their targets.; Dr. Guang Yang familiar with various disease areas, such as cancer, inflammatory, auto-immune, infectious, metabolic disorders, etc. He has a solid academic background, and has 20 years’ work experience in R&D department of global pharmaceutical companies and drug discovery institutes. The R&D team led by him obtained extraordinary achievements in the field of research and drugs discovery. He had established a wide range of cooperation with domestic and foreign partners.
**Thanks for Promega's Support on Lunch Session:
12:15-12:45 Lunch (Please book in advance for free lunch boxes)
12:45-13:15 ADCC Reporter Bioassay: A Novel, Bioluminescent Cell-Based Assay for Quantifying Fc Effector Function of Antibodies (Presented by Chang Liu, Ph.D, Promega(Beijing) Biotech Co.,Ltd)
Shuttle Bus:
合作媒体:
IRE1α-XBP1信号如今正在成为多种癌症类型中恶性肿瘤进展和免疫抑制的核心调节子;近日,一篇发表在国际杂志NatureCommunications上题为“Tumor-intrinsicIRE1αs......
自身免疫和自身炎症反应源于对自身成分的异常免疫和炎症反应,有助于各种自身免疫性疾病和自身炎症性疾病。RNA结合蛋白(RNA-bindingproteins,RBPs)是免疫细胞发育和功能所必需的,主要......
近日,兽医所动物腹泻病防控创新团队应用单细胞测序技术对猪流行性腹泻病毒(PEDV)感染后不同肠道细胞的功能改变进行了系统性分析,相关研究成果以题为“IdentificationofCellTypesa......
当现代人首次从非洲迁徙到西南太平洋的热带岛屿时,欢迎他们的是陌生而神秘的当地人——丹尼索瓦人以及新的病原体。但与当地人的繁衍,使新来者的免疫系统获得了一些应对新病原体的生存技巧——接受丹尼索瓦人提供的......
据极目新闻报道,25天,接触了20个“小阳人”,成功照顾5人“阳康”,自己还没有“阳”。宁夏银川24岁的小伙贺安(化名)认为自己距离“决赛”越来越近。此前,有媒体报道,美国佐治亚州56岁的约翰·霍利斯......
原文地址:http://news.sciencenet.cn/htmlnews/2022/12/491050.shtm我国现有超过1.8亿老年人患有各种慢性病,随着年龄增长,老年人的各组织器官生理代谢......
目前,手术、放化疗、靶向药物、免疫药物等多种治疗措施在肿瘤治疗领域各自发挥着重要作用。其中,靶向药物和免疫治疗以其优秀的疗效得到了广泛运用。为了取得更好的疗效,让更多的患者获益,目前将几种治疗策略联合......
近年来,最火的癌症治疗的方法,CAR-T免疫细胞疗法绝对是关注焦点。免疫细胞治疗的临床研究在全球如火如荼的开展,随着免疫疗法被大众所认识,免疫细胞的作用受到重视,那么免疫细胞存储有必要吗?近日,美国食......
孩子小抵抗力弱,总是免不了三天两头往医院跑,但有一些孩子却因免疫系统天生无法正常工作,特别容易出现反复感染,甚至每半个月就会去一次医院。这种病常发生在婴幼儿,严重者会威胁生命。近日,5岁的男孩聪聪(化......
11月29日,美国科学院院刊PNAS在线刊发了海洋所刘保忠课题组题为Themud-dwellingclamMeretrixpetechialissecretesendogenouslysynthesi......