WIKI资讯
WIKI资讯
Interactions between cells responsible for cell to cell adhesion also can communicate signals into the cellular interior, often involving interactions with cytoskeletal elements to produce changes in cell motility, migration, proliferation and shape. The cadherins are cell surface adhesion molecules that help form tight junctions between cells such as formation of epithelial cell layers. E-cadherin inactivation has b......阅读全文
The IL-2 receptor is a key component of immune signaling and is required for the activation, proliferation, and survival of T cells. This receptor is
Scanning the human genome with combinatorial transcription factor librariesPublished online: 18 February 2003, doi:10.1038/nbt794March 2003 Volume 21
ConclusionsQuorum-sensing signaling systems involving the interaction between a signaling peptide and its cognate histidine kinase receptor are widely
As with many cell-surface receptors, activation of the EGF receptor can result in receptor internalization through receptor-mediated endocytosis, dese
Carbohydrate Assay (Hancock Laboratory) (Accessible only by IE)This protocol is used to determine the relative amounts of LPS CHO present in a gi
The G-protein coupled receptor (GPCR) family transduces extracellular signals across the plasma membrane, activating cellular responses through a vari
Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) and Desert Hedgehog (Dhh), that play distinct and
BRCA1 and BRCA2 were identified genetically as breast cancer susceptibility genes when a single copy of the gene is mutated and are involved in the ce
Rac-1 is a small G-protein in the Rho family that regulates cell motility in response to extracellular signals. Several changes in cytoskeletal struct
The differentiation of muscle cells is transcriptionally regulated, in part by the myocyte enhancer factor-2, MEF2. During myogenesis MEF2 binds to My
The activation of T cells requires a co-stimulatory signal with T cell receptor activation, provided in many cases by activation of CD28 in resting T
IntroductionFetal Alcohol Syndrome (FAS) is caused by exposure of the developing embryo to alcohol, one of several teratogenic agents which adversely
Bead-array-based microRNA detection technology, including the bio-statistic analysis, is currently not well established or widely used and we have app
Four different members of the Sprouty protein family block the cellular proliferation and differentiation induced by several different growth factors,
实验概要Central neurons lose the ability for axonal regrowth during development and typically do not regenerate their axons following axotomy once the
CSP-Dependent Transformation AssayTo determine if synthetic peptides activated quorum sensing for induction of genetic competence, we used the co
Interaction of T cell receptor with specific antigen in the context of MHC II activates a signal transduction pathway that leads to T cell activation.
获得性免疫具有记忆效应。免疫系统在感染之后发展出的长期记忆T细胞可以应对未来感染。这些记忆T细胞具有干细胞性质。最近研究已经证实了在慢性感染中耗竭性CD8+ T细胞中，存在着一种独特的干细胞样的T细胞亚群【1】。然而，在慢性感染情况下，CD4+ T细胞是否也有类似性质的亚群仍不清楚。TH17细胞
IL-7 is a key cytokine in the immune system, essential for normal development of B cells and T cells. Mice with the IL-7 receptor deleted lack B and T
Abstract Choriallantoic membrane (CAM) limb grafting functions as a method to isolate the inductive eve
ObjectiveThe purpose of this experiment is to determine the effects of calcium-free seawater on the development of sea urchin embryos. Embryos were pl
MTT Assay on Reattached CellsAs seen in Fig. 2 , the proportion of viable MSC that re-attached was significantly higher (p
TNF acts on several different signaling pathways through two cell surface receptors, TNFR1 and TNFR2 (See TNFR1 and TNFR2 Signaling Pathways) to regul
GREATER GENEVA BERNE area (GGBa) GREATER GENEVA BERNE area (GGBa) is an Economic Development Agency complementary to BioAlps ‘s mission offerin
Many transcription factors play essential roles in normal development by determining the proliferation and differentiation of cells. The coordinated t
Our experience indicates that it may not be sufficient to change the medium containing Rottlerin and to wash the cells before adding MTT to avoid a po
引言：上海吉凯基因化学技术有限公司成立于2002年，拥有国内最大的慢病毒文库，同时也是国内最大的疾病关键基因科研服务供应商，在疾病研究领域的实验积累已逾14年！在这里，我们为大家特别整理了10多个研究领域的经验所得，将最实用的精华分享给大家！上一期帮大家总结了肺癌研究中慢病毒工具的应用，上期回顾看这
Cytokine BioassaysIntroductionBiological activity of cytokines and their concentrations are commonly measured by cellular proliferation of primary cel
Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental factor. Shh provides a morphogenic signal in the devel
截止2020月7月27日，中国学者在Cell，Nature 及Science 发表了共计102项生命科学的研究成果，其中新冠肺炎领域占了近一半（共43篇）。iNature系统总结了这些研究成果： 按杂志来划分：Cell 发表了30篇，Nature 发表了45篇，