WIKI资讯
WIKI资讯
The focus of this pathway is to illustrate the role of Polo-like Kinase 3 (Plk3 also known as Prk and Fnk) as part of the regulatory cascade leading to apoptosis and the arrest cell cycle progression prior to M phase. Phosphorlyation of Cdc25C on serine-216 causes the arrest of the cell cycle at the G2/M phase border by preventing Cdc25C from activating cyclinB1/Cdk1. Xie et al. demonstrated that Plk3 like Chk1 and C......阅读全文
Cyclins are proteins that associate with cyclin-dependent protein kinases to regulate their activity and the progression of the cell cycle through spe
Terminal differentiation of cells is often accompanied by repression of cellular proliferation, suggesting that there is a mechanism by which these ce
While transcriptional regulation is often viewed as the most prevalent way extracellular signals to regulate gene expression, post-transcriptional reg
The cell cycle transition from G1 to S phase is a key regulatory point in the cell cycle. This transition is regulated by the checkpoint kinase cdk2 t
Sonic Hedgehog (Shh) is one of a family of three secreted proteins, including Indian Hedgehog (Ihh) and Desert Hedgehog (Dhh), that play distinct and
2.2 Interaction mating - large scaleWith a few modifications, the procedure described above can be used to test for interactions between a single prey
p27/Kip1 regulates the cell cycle by inhibiting the checkpoint kinase cdk2/cyclin E and blocking cell cycle progression through the G1-S transition. C
Progression through the cell cycle is accompanied by activation of the proto-oncogene c-Src, a protein tyrosine kinase. Overexpression of Src leads to
E2F-1 is a transcription factor that regulates the expression of genes involved in the cell cycle and that is involved in progression of the cell cycl
Cell cycle checkpoint controls at the G1 to S transition and the G2 to M transition prevent the cell cycle from progressing when DNA is damaged. The A
The PML nuclear bodies are ring-shaped nuclear substructures associated with the regulation of transcription, transformation, cell growth, and apoptos
Figure 5: Regulation of CDH5 by TFZFs in several human cancer cell lines.Blue, cells infected with a pMX construct containing the DNA bindin
FL3500双调制叶绿素荧光仪 （新升级型号为FL6000） FL3500双调制叶绿素荧光仪是专门用于对蓝绿藻或绿藻等微藻，叶绿体或类囊体悬浮物，乃至叶片进行光合作用研究的强大科研工具。仪器具备双通道测量控制，可控制测量样品的温度，并配备单翻转光（STF），内置多种可用户自行修改的测量程序
Sonic Hedgehog (Shh) is a secreted protein identified genetically as an important developmental factor. Shh provides a morphogenic signal in the devel
The hepatocyte growth factor receptor, also called c-Met, is activated by HGF and stimulates proliferation of hepatocytes and other cell types. Mutate
The chromatin packaging of the genome is dynamic, changing with the cell cycle and with transcriptional regulation. During mitosis, chromatin is conde
截至2019年12月23日，中国学者在Cell，Nature及Science在线发表了107篇文章（2019年的Cell ，Nature 及Science 已经全部更新），iNature团队对于这些文章做了系统的总结： 按杂志来划分：Cell 发表了31篇，Nature 发表了44篇，Scie
ANALYSIS OF CELL CYCLE Miriam Capri and Daniela Barbieri Dept. Biomedical Sciences, Sect. General Pathology,Via Campi, 287, University of Mo
Scanning the human genome with combinatorial transcription factor librariesPublished online: 18 February 2003, doi:10.1038/nbt794March 2003 Volume 21
FluidFM 测定细胞粘附力的应用随着时间推移，越来越多的学者开始使用FluidFM 技术进行测定细胞粘附力。以下就近五年的具有代表性的应用进行总结。Cohen 等使用FluidFM 技术对MCF7-MCF10A、MCF7-HS5 的细胞粘附力进行了测定，并与以往的文献进行对比，发现其数据与Hos
References1. Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA: a cancer journal for clinician
Cyclin-dependent kinase inhibitor-2A (CDKN2A) goes by the colloquial designation p16, which is sometimes referred to as p16(INK4). The alpha transcrip
The plasticity of differentiated adult cells could have a great therapeutic potential, but at the same time, it is characteristic of progression of se
Eukaryotic cells take up constituents of the extra-cellular environment and regulate the cell-surface level of membrane proteins via a recycling syste
DNA and RNA Staining6. Stain cells with 7-AAD: i. Resuspend the cells from Step 5 in 0.5 mL of NASS containing 10 µg/mL of 7-AAD. Incub
2019年上半年很快就结束了，iNature盘点了中国学者在Cell，Nature及Science发表的成果，我们发现总共有86篇（截至2019年6月24日），具体介绍如下： 4-6月发表的文章 【1】2019年6月21日，西北工业大学王文，中科院昆明动物研究所/BGI 张国捷及丹麦哥本哈根
截至2019年12月13日，中国学者在Cell，Nature及Science在线发表了105篇文章（2019年的Cell已经全部更新完毕，而对于Nature及Science只剩下了一期，将分别会12月19日及20日进行更新），小编对于这些文章做了系统的总结： 按杂志来划分：Cell 发表了30
截至2019年12月31日，中国学者在Cell，Nature及Science在线发表了186篇文章，其中生命科学领域有109篇，材料学有30篇，物理学有20篇，化学有12篇，地球科学有15篇。iNature团队对于这些文章做了系统的总结： 按杂志来划分：Cell 发表了31篇，Nature 发
Over 1,000 papers and reviews have been written about the role of ceramide in the production of programmed cell death or apoptosis. Ceramide is a sphi