Covalent attachment of one eukaryotic protein to another is a prominent posttranslational modification and Ubiquitin is the most familiar of the protein modifiers. Recently a new group of ubiquitin-like (Ubl) proteins have come to light. One of the most intriguing of them is SUMO (small ubiquitin-like modifier, ~12kDa) also known as Sentrin. SUMO family has been described in vertebrates: SUMO-1 and the closest homolo......阅读全文
FL3500双调制叶绿素荧光仪 (新升级型号为FL6000) FL3500双调制叶绿素荧光仪是专门用于对蓝绿藻或绿藻等微藻,叶绿体或类囊体悬浮物,乃至叶片进行光合作用研究的强大科研工具。仪器具备双通道测量控制,可控制测量样品的温度,并配备单翻转光(STF),内置多种可用户自行修改的测量程序
MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2aMicroRNAs are positive and negative r
The role of Hemophilus influenzae in ear infections and chronic obstructive pulmonary disease includes the induction of an inflammatory response throu
FIG. 4.Aberrant gene expression patterns of cardiac remodeling factors in ARKO male mice with or without Ang II stimulation. The left panel demons
John “JC” Carver, a payload integration engineer with NASA Kennedy Space Center’s Test and Operations Support Contract, uses a FluorPen to measure
Signaling by interferon-gamma stimulates anti-viral responses and tumor suppression through the heterodimeric interferon-gamma receptor. Signaling is
Hypoxia (or low O2 levels) affects various pathologies. First, tissue ischemia, a variation in O2 tension caused by hypoxia/reoxygenation, can lead to
The drug Gleevec (also known as imatinib mesylate or STI-571) was approved by the FDA in 2001 for the treatment of CML, chronic myeloid leukemia. Whil
ContentsEmbryonic Stem Cell MarkersHematopoietic Stem Cell MarkersMesenchymal/Stromal Stem Cell MarkersNeural Stem Cell MarkersReferencesWhile stem ce
第一版(2010年9月)前言 医学论文设计水平的新颖性和创新性,是决定撰写的医学论文能否被SCI医学杂志编委和主编认同的第一门道;医学论文撰写水平的逻辑性和规范性,则是决定撰写的医学论文能否被SCI医学杂志接受的最终门道。发表SCI期刊医学论文的语言是英语,对于母语是非英语的中国临床医生
第一版(2010年9月)前言 医学论文设计水平的新颖性和创新性,是决定撰写的医学论文能否被SCI医学杂志编委和主编认同的第一门道;医学论文撰写水平的逻辑性和规范性,则是决定撰写的医学论文能否被SCI医学杂志接受的最终门道。发表SCI期刊医学论文的语言是英语,对于母语是非英语的中国临床医生
简明SCI期刊医学论文撰写手册 第一版(2010年9月)前言 医学论文设计水平的新颖性和创新性,是决定撰写的医学论文能否被SCI医学杂志编委和主编认同的第一门道;医学论文撰写水平的逻辑性和规范性,则是决定撰写的医学论文能否被SCI医学杂志接受的最终门道。发表SCI期刊医学论文的语言
实验概要Environmental stresses often trigger rapid generation of reactive oxygen species (ROS) in plants. Excessive amount of ROS can cause damage to
Exalpha Biologicals produces and sells products for Life Science Research, including monoclonal and polyclonal antibodies, for use in immunohistochemi
截止2020月7月27日,中国学者在Cell,Nature 及Science 发表了共计102项生命科学的研究成果,其中新冠肺炎领域占了近一半(共43篇)。iNature系统总结了这些研究成果: 按杂志来划分:Cell 发表了30篇,Nature 发表了45篇,
Scanning the human genome with combinatorial transcription factor librariesPublished online: 18 February 2003, doi:10.1038/nbt794March 2003 Volume 21
One mechanism used by cytotoxic T cells to kill tumor cells and virus-infected cells is the release of perforin and granzyme proteins. Perforin protei
cDNA LibrariesIsolation of corresponding genetic informationInstead of synthesizing a desired gene, can we used the amino acid information to directly
For direct gene transfer of tibialis anterior (TA) muscle in mice: It is optimal to use 6-8 week old mice (weight 19-21 gm). Females give better immun
实验概要A novel impulsive cell pressurization experiment has been developed using a Kolsky bar device to investigate blast-induced traumatic b
ASTRACTWe describe a rapid and quantitative flow cytometric method for determining the apoptotic or anti-apoptotic potential of a gene in various cell
The most recognized mechanism by which peroxisome proliferators regulated gene expresssion is through a PPAR/RXR heterodimeric complex binding to a pe
Argonaute - A family of proteins containing multiple domains and involved in RNA interference (RNAi). Argonatue is the main component of RNAi eff
Macrophages and NK cells help provide innate immunity against infection by intracellular parasites and communicate with each other to regulate this pr
RNAi GlossaryDicer - Dicer is a member of the RNase III family of nucleases that specifically cleave double-stranded RNAs. Dicer processes long d
Interleukin-6 Induced Acute Phenotypic Microenvironment Promotes Th1 Anti-Tumor ImmunityTing Xue1, Ping Liu1, Yong Zhou2, Kun Liu1, Li Yang2, Robert L
WHENVIRUSESINFECTEUKARYOTICCELLSdomly integrate into host genomes, double-stranded RNA (dsRNA) is frequently produced from the invading genes, either
Nuclear hormone receptors are transcription factors that bind DNA and regulate transcription in a ligand-dependent manner. PPAR-gamma is a member of t
IntroductionFetal Alcohol Syndrome (FAS) is caused by exposure of the developing embryo to alcohol, one of several teratogenic agents which adversely
随着人类基因组计划(human genome project )在2003年顺利完成,基因组测序技术取得了长足的进步,这直接导致了每兆基因组成本的大幅下降以及检测的基因组数量越来越多。人们对基因组的复杂性深感震惊,这也引导着测序技术的进一步发展。最近的一些突破性技术使得测序技术在更短的时间内可以