ControlofGeneExpressionbyVitaminDReceptor
The vitamin D receptor, VDR is the mediator of all genomic actions of vitamin D3 and its analogs. It belongs to a family of ligand induced transcription factors, nuclear receptors (NRs). Vitamin D3 is the main regulator of calcium homeostasis and is critical in bone formation. It is also involved in controlling cellular growth, differentiation and apoptosis, which makes synthetic vitamin D3 analogues interesting for ......阅读全文
Control－of－Gene－Expression－by－Vitamin－D－Receptor
The vitamin D receptor, VDR is the mediator of all genomic actions of vitamin D3 and its analogs. It belongs to a family of ligand induced transcripti
FOSB－gene－expression－and－drug－abuse
Drug addiction is associated with long-term behavioral changes, suggesting a long-lived transcriptional regulator that responds to chronic drug exposu
Double－Stranded－RNA－Induced－Gene－Expression
One defense against viral infection is provided by PKR, double-stranded RNA activated protein kinase. When PKR interacts with dsRNA found in cells dur
PCR－Primers－For－Gene－Expression－Detection－or－Quantification
Why PrimerBank?PrimerBank is a public resource for PCR primers. These primers are designed for gene expression detection or quantification (real-time
Gene－Expression－Analysis－of－Shoot－Apical－Meristem－Cell－Types
Shoot apical meristems (SAMs) of higher plants harbor a set of stem-cells and provide cells for the development of all the above-ground biomass of
克隆基因的表达（expression－of－cloned－gene）1
基因表达(gene expression)是指储存遗传信息的基因经过一系列步骤表现出其生物功能的整个过程。典型的基因表达是基因经过转录、翻译，产生有生物活性的蛋白质的过程。基因的表达主要涉及到两个过程：转录和翻译。 第一节影响外源基因表达的因素 利用基因工程技术高水平表达
克隆基因的表达（expression－of－cloned－gene）2
在双链 DNA 分子中，只有一条链转录成 mRNA，这条链称为有意义链(sense strand)，该基因的另一条链则称反意义链(antisense strand)。在含有许多基因的 DNA 双链中，每个基因的有意义链并不是在同一条 DNA 链上。也就是说，一条链上既具有某些基因的有意义链，
克隆基因的表达（expression－of－cloned－gene）3
（3）原核生物的基因组基本上是单倍体，而真核基因组是二倍体。（4）如前所述，细菌多数基因按功能相关成串排列，组成操纵元的基因表达调控的单元，共同开启或关闭，转录出多顺反子(polycistron)的mRNA；真核生物则是一个结构基因转录生成一条mRNA，即mRNA是单顺反子(monocistron)
Heterogeneity－of－SingleCell－Gene－Expression－Across－Phenotypically（一）
Introduction Multi-cellular populations are fundamentally driven by the collective properties of individual cells. However, our understanding of ge
fMLP－induced－chemokine－gene－expression－in－HMC1－cells
Neutrophils respond to bacterial infection by releasing reactive oxygen species that kill bacteria and by expressing chemokines that attract other imm
Oxidative－Stress－Induced－Gene－Expression－Via－Nrf2
Reactive oxygen species (ROS) can damage biological macromolecules and are detrimental to cellular health. Electrophilic compounds, xenobiotics and an
Heterogeneity－of－SingleCell－Gene－Expression－Across－Phenotypically（二）
Figure 2: Verification of C1 Single-Cell mRNA-Seq data quality. a)ERCC RNA Spike-In Control Mix 1 was applied to a C1 IFC at a total transcript in
RARB基因编码的功能和结构描述
这个基因编码维甲酸受体β，它是核转录调控因子甲状腺类固醇激素受体超家族的成员。这种受体定位于细胞质和亚核室。它与维生素a的生物活性形式维甲酸结合，维甲酸介导胚胎形态发生、细胞生长和分化的细胞信号。人们认为这种蛋白质通过调节基因表达来限制许多细胞类型的生长。该基因首先在一个肝细胞癌中被发现，它位于乙型
RARB基因突变因子与药物介绍
这个基因编码维甲酸受体β，它是核转录调控因子甲状腺类固醇激素受体超家族的成员。这种受体定位于细胞质和亚核室。它与维生素a的生物活性形式维甲酸结合，维甲酸介导胚胎形态发生、细胞生长和分化的细胞信号。人们认为这种蛋白质通过调节基因表达来限制许多细胞类型的生长。该基因首先在一个肝细胞癌中被发现，它位于乙型
Nuclear－Receptors－in－Lipid－Metabolism－and－Toxicity
Nuclear receptors are transcription factors that are activated upon binding to its ligands. Initially, they had been classified as classic endocrine n
RTPCR在基因表达（gene－expression）检测中的应用
基因表达的检测有几种方法。经典的方法（仍然重要）是根据在细胞或生物体中 所观察到的生物化学或表型的变化来决定某一特定基因是否表达。随着大分子分离技 术的进步使得特异的基因产物或蛋白分子的识别和分离成为可能。随着重组DNA技术 的运用，现在有可能检测．分析任何基因的转录产物。目前有好几种方
无创血压计应用论文：动物用血压计（五）
FIG. 4.Aberrant gene expression patterns of cardiac remodeling factors in ARKO male mice with or without Ang II stimulation. The left panel demons
Vitamin－C－in－the－Brain
Vitamin C (ascorbic acid) was first identified by virtue of the essential role it plays in collagen modification, preventing the nutritional deficienc
Visual－Signal－Transduction
The signal transduction cascade responsible for sensing light in vertebrates is one of the best studied signal transduction processes, and is initiate
Multistep－Regulation－of－Transcription－by－Pitx2
Many transcription factors play essential roles in normal development by determining the proliferation and differentiation of cells. The coordinated t
siRNAs结合生物芯片的实验设计2
Figure 2. Silencer ™ siRNA Validation Data Generated Using Applied Biosystems TaqMan® Gene Expression Assays. The indicated Silencer Validated siRNAs
A－Method－for－Structure4
We also used this mutant (SMdC) as a host to generate two types of lacZ transcriptional reporter fusion strains to assay the promoter activity of QS-c
Competitive－RTPCR－Strategy－for－Quantitative－Evaluation－1
Competitive RT-PCR Strategy for Quantitative Evaluation of the Expression of Tilapia (Oreochromis niloticus) Growth Hormone Receptor Type IQuantizatio
Pest－Control
We use Dimilin G (4% diflubenzuron) from Maag AG to fight the small dipteran black flies (Trauermücken). It is a granular substance and sprinkled
定量RTPCR－（Quantitative－RTPCR）
Application: Quantitative RT-PCR is used to quantify mRNA in both relative and absolute terms. It can be applied for the quantification of mRNA expres
FGFR－INHIBITOR,－SU5402,－ON－CRANIOFACIAL－DEVELOPMENT－IN－CHICKEN－EMBRYOS
ABSTRACTFibroblast growth factor (FGF) signaling plays a signifigant role in embryonic development. Particularyl, FGFs are implicated in mediating epi
无创血压计应用论文：动物用血压计（一）
Androgen Receptor Gene Knockout Male Mice Exhibit Impaired Cardiac Growth and Exacerbation of Angiotensin II-induced Cardiac Fibrosis 【摘要】 Androg
Downregulated－of－MTA3－in－ERnegative－Breast－Tumors
Approximately 30% of breast carcinomas lack ER expression. Presumably, these breast cancers become estrogen independent through genetic alterations th
siRNAs结合生物芯片的实验设计1
Ambion and Applied Biosystems have joined forces to provide a complete convenient, solution for performing gene silencing experiments and validating t
GentleMACS/单细胞悬液制备文献集锦
种属 处理组织 文章名称 human