SizeandShapeofProteinMolecules1
Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron MicroscopyAn important part of characterizing any protein molecule is to determine its size and shape. Sedimentation and gel filtration are hydrodynamic techniques that can be used for this medium resolution structural analysis. This review collects a number of simple calculations that are useful for t......阅读全文
Size-and-Shape-of-Protein-Molecules5
Hydrodynamic Analysis and EM Applied to Large Multisubunit ComplexesThe text box above showed the application of the Siegel–Monte analysis to SMC prot
Size-and-Shape-of-Protein-Molecules2
The sedimentation coefficient of a protein is a measure of how fast it moves through the gradient. Increasing the mass of the protein will increase it
Size-and-Shape-of-Protein-Molecules4
Determining the Molecular Weight of a Protein Molecule—Combining S and R s à la Siegel and MonteWith the completion of multiple genomes and increasing
Size-and-Shape-of-Protein-Molecules1
Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron MicroscopyAn important part of ch
Size-and-Shape-of-Protein-Molecules3
The Kirkwood/Bloomfield CalculationThe understanding of how protein shape affects hydrodynamics is elegantly extended by an analysis originally develo
Size-and-Shape-of-Protein-Molecules5
Hydrodynamic Analysis and EM Applied to Large Multisubunit ComplexesThe text box above showed the application of the Siegel–Monte analysis to SMC prot
Structure-of-Mitochondria
The cytoplasm of nearly all eukaryotic cells contain mitochondria, although there is at least one exception, the protist Chaos (Pelomyxa) carolinensis
Protein-Electrophoresis
DefinitionAmino acids, nucleotides, polypeptides, and other compounds in a colloidal state can be separated by the application of external voltages wh
Mitochondria-Structure-and-Function--Theoretical-Details
Mitochondria Structure and Function - Theoretical DetailsIn an attempt to be concise and understandable, introductory level courses and textbooks freq
线粒体的结构与功能
In an attempt to be concise and understandable, introductory level courses and textbooks frequently present concepts that are technically correc
Lipoprotein-Analysis-Week-2:-Electrophoresis
Lipoprotein Analysis Week 2: Electrophoresis IntroductionSDS polyacrylamide gel electrophoresis (SDS PAGE) will be used to assess the purification pr
Cell-to-Cell-Adhesion-Signaling
Interactions between cells responsible for cell to cell adhesion also can communicate signals into the cellular interior, often involving interactions
Adhesion-Molecules-on-Lymphocyte
B cell and T cell lymphocytes interact with a variety of cells as part of their immune function, circulating and homing in on specific stimuli in tiss
Integrin-Signaling-Pathway
Integrins are cell surface receptors that interact with the extracellular matrix and mediate intracellular signals in response to the extracellular ma
Neutrophil-and-Its-Surface-Molecules
Neutrophils are important phagocytotic leukocytes (white blood cells) that internalize and destroy infectious bacteria by a respiratory burst of react
Monocyte-and-its-Surface-Molecules
Monocytes are a class of phagocytes involved in non-specific immune defense that develop into macrophages. In plasma, monocytes ingest and destroy bac
石墨烯在太赫兹频段实现的无线片上网络(WiNoC)(三)
3.2. Molecular Absorption Attenuation (MAA)As the electromagnetic wave at frequency passes through a transmission medium of distance , there exists a
生物技术等级透析膜应用介绍
At one time or another most scientists working in the ‘biochemical’ sciences will have to dialyze something. Dialysis is a simple technique to exc
Native-gel-electrophoresis(非变性电泳)
Native gel electrophoresis Under native PAGE conditions, polypeptides retain their higher-order structure and often retain enzymatic activity and inte
DNA-Electrophoresis
What is Electrophoresis?Electrophoresis is a technique used in the laboratory that results in the separation of charged molecules. DNA is a negatively
Antibody-Purification-using-Protein-A,-Protein-G,-or-Protein-L-Agarose
实验概要This protocol is designed as a quick purification method for antibodies from mammalian sera, ascites, and cell culture supernatants. It should
Antibody-Purification-using-Protein-A,-Protein-G,-or-Protein-L-Agarose
实验概要This protocol is designed as a quick purification method for antibodies from mammalian sera, ascites, and cell culture supernatants主要试剂 Protein
B-Lymphocyte-Cell-Surface-Molecules
B cells must communicate with their environment to participate in the immune system as the source of antigen-specific immunoglobulins. Cell surface pr
T-Helper-Cell-Surface-Molecules
T helper cells play an essential role coordinating the activities of other parts of the immune system, including B cells, cytotoxic T cells, macrophag
T-Cytotoxic-Cell-Surface-Molecules
Cytotoxic T cells are a key part of the cellular immune response, killing cells that display foreign antigen on their surface, primarily virus-infecte
与乳腺癌相关的PTPN12基因编码功能描述
该基因编码的蛋白是蛋白酪氨酸磷酸酶(PTP)家族的成员。PTP是调节多种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和致癌转化。这个ptp包含一个c-末端害虫基序,作为一个蛋白质-蛋白质相互作用域,可以调节蛋白质的细胞内半衰期。这种PTP被发现与癌基因c-abl的产物结合并去磷酸化,因此可能
与肺癌相关的PTPN12基因编码功能描述
该基因编码的蛋白是蛋白酪氨酸磷酸酶(PTP)家族的成员。PTP是调节多种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和致癌转化。这个ptp包含一个c-末端害虫基序,作为一个蛋白质-蛋白质相互作用域,可以调节蛋白质的细胞内半衰期。这种PTP被发现与癌基因c-abl的产物结合并去磷酸化,因此可能
PTPN12基因突变因子与药物介绍
该基因编码的蛋白是蛋白酪氨酸磷酸酶(PTP)家族的成员。PTP是调节多种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和致癌转化。这个ptp包含一个c-末端害虫基序,作为一个蛋白质-蛋白质相互作用域,可以调节蛋白质的细胞内半衰期。这种PTP被发现与癌基因c-abl的产物结合并去磷酸化,因此可能
PTPN12基因编码的功能和结构描述
该基因编码的蛋白是蛋白酪氨酸磷酸酶(PTP)家族的成员。PTP是调节多种细胞过程的信号分子,包括细胞生长、分化、有丝分裂周期和致癌转化。这个ptp包含一个c-末端害虫基序,作为一个蛋白质-蛋白质相互作用域,可以调节蛋白质的细胞内半衰期。这种PTP被发现与癌基因c-abl的产物结合并去磷酸化,因此可能
Radioiodination-of-protein
Radioiodination (by Jun Takagi,6/16/2000)Purpose and backgroundsPrinciple of radioiodinationAddition of oxidizing reagents (such as chloramine-T or pe