MitochondriaStructureandFunctionTheoreticalDetails
Mitochondria Structure and Function - Theoretical DetailsIn an attempt to be concise and understandable, introductory level courses and textbooks frequently present concepts that are technically correct, but lead to misconceptions on the part of the student because they omit too much. In discussions about mitochondria students frequently come away with a superficial understanding of the true nature of Krebs' cycl......阅读全文
Mitochondria－Structure－and－Function－－Theoretical－Details
Mitochondria Structure and Function - Theoretical DetailsIn an attempt to be concise and understandable, introductory level courses and textbooks freq
Structure－of－Mitochondria
The cytoplasm of nearly all eukaryotic cells contain mitochondria, although there is at least one exception, the protist Chaos (Pelomyxa) carolinensis
线粒体的结构与功能
In an attempt to be concise and understandable, introductory level courses and textbooks frequently present concepts that are technically correc
Regulation－And－Function－Of－ChREBP－in－Liver
Liver is the major site for carbohydrate metabolism (glycolysis and glycogen synthesis) and triglyceride synthesis (lipogenesis). While insulin was lo
Recommended－Experiments－with－Isolated－Mitochondria
In our teaching lab we encourage students to work with each other and to share insight, experience, and even experimental results. To facilitate such
Role－of－Mitochondria－in－Apoptotic－Signaling
Mitochondria participate in apoptotic signaling pathways through the release of mitochondrial proteins into the cytoplasm. Cytochrome c, a key protein
Apoptotic－DNA－fragmentation－and－tissue－homeostasis
Apoptotic cell death can be triggered by many different cellular stimuli, resulting in activation of apoptotic signaling pathways including caspases (
Function－of－SLRP－in－Bone:－An－Integrated－View
SLRPs (Small leucine-rich proteoglycans) are extracellular molecules that bind to TGF-betas, collagens and other matrix molecules. In vitro, SLRPs wer
Reverse－Transfection－for－Gene－Function－Analysis
This guide describes a microarray-based system for the functional analysis in mammalian cells of many genes in parallel. Mammalian cells are cultured
Preparation－of－Mitochondria－from－Rat－Liver
Preparation of Mitochondria from Rat LiverRat liver is an ideal source for functional intact mitochondria for a number of reasons. We use Sprague-Dawl
Preparing－Mitochondria－from－Rat－Liver
Liver is a convenient source for functional intact mitochondria for a number of reasons. Animal tissue is more readily homogenized than plant tissue b
线粒体荧光探针大全：TMRM，Mitotracker，JC1（1）
线粒体荧光探针信息大全 （Probes for Mitochondria）包括各种常用探针，如JC-1，JC-9，TMRM，TMRE等Mitochondria are found in eukaryotic cells, where they make up as much as 10% of th
whats－the－function－of－compressed－air－filter
Compressed air is an essential utility in many industrial applications, including pneumatic tools, packaging, and conveying systems. It is a clean, ef
A－Method－for－Structure5
ConclusionsQuorum-sensing signaling systems involving the interaction between a signaling peptide and its cognate histidine kinase receptor are widely
A－Method－for－Structure3
CSP-Dependent Transformation AssayTo determine if synthetic peptides activated quorum sensing for induction of genetic competence, we used the comC de
A－Method－for－Structure2
CD SpectroscopyCD spectra for peptides and reference solutions were recorded at 298 K on a Jasco J-920 CD spectrometer with a 1-mm quartz cuvette. Spe
A－Method－for－Structure1
A Method for Structure–Activity Analysis of Quorum-Sensing Signaling Peptides from Naturally Transformable StreptococciMany species of streptococci se
Gene－Structure－Annotation－at－PlantGDB
The accurate identification of exons and introns that comprise a complete plant gene structure can be a time-consuming and challenging task. Novel
A－Method－for－Structure4
We also used this mutant (SMdC) as a host to generate two types of lacZ transcriptional reporter fusion strains to assay the promoter activity of QS-c
抗体结构（antibody－structure）
抗体（antibody，Ab）是机体免疫细胞被抗原激活后，由分化成熟的终末B细胞--浆细胞合成、分泌的一类能与相应抗原特异性结合的具有免疫功能的球蛋白。 抗体是具有4条多肽链的对称结构，其中2条较长、相对分子量较大的相同的重链（H链），含450?550个氨基酸残基，相对分子质量在 55000?7
Recommended－Experiments－with－Isolated－Mitochondria2
2. Respiratory control on glutamate and inhibition of electron transportAdd 30-40 µl mitochondria, obtain a steady state. We use a larger volume tha
Comparison－of－Beta－oxidation－in－mitochondria－and－peroxisomes－andglyoxysomes
In addition to the beta-oxidation of fatty acids in mitochondria, animal cells carry out beta-oxidation in another organelle, the peroxisome. Although
Shuttle－for－transfer－of－acetyl－groups－from－mitochondria－to－the－cytosol
Acetyl-CoA is produced in mitochondria through the metabolism of fatty acids and the oxidation of pyruvate to acetyl-CoA. When ATP is needed, this ace
线粒体荧光探针大全：TMRM，Mitotracker，JC1（2）
MitoTracker Green FM ProbeMitochondria in cells stained with nanomolar concentrations of our patented MitoTracker Green FM dye (M7514) exhibit bright
Induction－of－apoptosis－through－DR3－and－DR4/5－Death－Receptors
Apoptosis is specifically induced via signaling through a family of receptors known collectively as 'death receptors' including Fas, TNFR, DR3
Angiotensinconverting－enzyme－2－regulates－heart－function
Cardiovascular diseases are predicted to be the most common cause of death worldwide by 2020. The major regulator of blood pressure homeostasis is the
Structure：损伤DNA末端降解过程机制
2022年7月15日，浙江大学生命科学学院赵烨教授、华跃进教授联合浙江大学医学院郭江涛教授团队在CellPress旗下的Structure杂志发表了题为“Mechanisms of helicase activated DNA end resection in bacteria”的研究成果。该论文使
Structure封面文章：解密白内障的形成
白内障是致盲的第一杀手，目前世界上有近两千万人受到它的影响。日前，加州大学Irvine分校的科学家们取得了重要成果，揭开了白内障的形成机制，这一成果将有望帮助人们为白内障患者恢复视力。这项研究作为封面文章刊登在十二月的Structure杂志上。 “我们的研究阐述了白内障形成的分子机制，这一
Structure：猫咪帮助找寻抗HIV新药物
如果你最近还没有为你的猫咪做检查，那你也可能不知道你的猫咪可能感染了艾滋病毒。猫免疫缺陷病毒肯能会引起猫咪致病，其症状类似感染HIV病毒后的症状。但是科学家认为这是研究抗HIV新药的一种契机。 猫咪会怎么帮助人们抗击艾滋病呢？不管是猫免疫缺陷病毒（FIV)还是人免疫缺陷病毒都会依赖一种称为整合
蛋白质结构预测(protein－structure－prediction)
一种生物体的基因组规定了所有构成该生物体的蛋白质，基因规定了组成蛋白质的氨基酸序列。虽然蛋白质由氨基酸的线性序列组成，但是，它们只有折叠成特定的空间构象才能具有相应的活性和相应的生物学功能。了解蛋白质的空间结构不仅有利于认识蛋白质的功能，也有利于认识蛋白质是如何执行其功能的。确定蛋白质的结构对于生物