NeutrophilandItsSurfaceMolecules
Neutrophils are important phagocytotic leukocytes (white blood cells) that internalize and destroy infectious bacteria by a respiratory burst of reactive oxygen species and by enzymatic digestion. Along with macrophages, neutrophils are crucial phagocytotic cells of the immune system and also contribute to anti-viral defenses, binding to and eliminating free virus or virus-infected cells. The presence of cytoplasmic ......阅读全文
NCF4基因突变与药物因子介绍
由该基因编码的蛋白质是超氧化物产生吞噬细胞NADPH氧化酶的细胞质调节成分，是一种重要的宿主防御的多组分酶系统。这种蛋白优先在髓系细胞中表达它主要与中性粒细胞胞质因子2（ncf2/p67-phox）相互作用，形成与中性粒细胞胞质因子1（ncf1/p47-phox）的复合物，并与小g蛋白rac1进一步
NCF4基因编码功能及结构描述
由该基因编码的蛋白质是超氧化物产生吞噬细胞NADPH氧化酶的细胞质调节成分，是一种重要的宿主防御的多组分酶系统。这种蛋白优先在髓系细胞中表达它主要与中性粒细胞胞质因子2（ncf2/p67-phox）相互作用，形成与中性粒细胞胞质因子1（ncf1/p47-phox）的复合物，并与小g蛋白rac1进一步
Classical－Complement－Pathway
The complement system is part of the defense against invading cells and is composed of about twenty different proteins found in the plasma. When activ
Application－Note:－Qdot®－Nanocrystal－Conjugates－in－Flow－Cytometry
实验概要Researchers today are trying to maximize the information that they get out of flow cytometry experiments by looking at more parameters in a sing
Realspace－and－realtime－dynamics－of－CRISPRCas9－visualized－by－...（三）
Fig. 4Structural rearrangement of the HNH domain. a, b HS-AFM images of the HNH domain in the high-height (a) and low-height (b) states. The mean ce
IL22－Soluble－Receptor－Signaling－Pathway
IL-22 is an inflammatory cytokine related to IL-10 that is produced by T cells and that induces a response in cells through a heterodimeric cell surfa
Cell－to－Cell－Adhesion－Signaling
Interactions between cells responsible for cell to cell adhesion also can communicate signals into the cellular interior, often involving interactions
Fluorescent－Nucleoside－Triphosphates－for－SingleMolecule－Enzymology1
By: Christopher P. Toseland1 2 , Martin R. Webb1Affiliation(s): (1) MRC National Institute for Medical Research, London, UK(2) Institut für Zelluläre
RNAi相关的名词解释[英文]
Argonaute - A family of proteins containing multiple domains and involved in RNA interference (RNAi). Argonatue is the main component of RNAi effector
BhPD1/hBTLA双人源化小鼠
BTLA基因功能B细胞和T细胞衰减蛋白（B and T lymphocyte associated，BTLA）是另一种Ig超家族的检查点负调分子，在结构上和CTLA4及PD-1类似，不仅表达于B细胞、T细胞、NK细胞，在树突状细胞和巨噬细胞中也有表达。BTLA与其配体HVEM（肿瘤坏死因子受体超家族
BLOCKiT－RNAi－Designer
Allows you to design synthetic siRNA, Stealth RNA, or shRNA molecules from nucleotide target sequences, or convert an siRNA molecule sequence into a S
ADPRibosylation－Factor
ADP-ribosylation factors (ARFs) are 20-kDa guanine nucleotide-binding proteins, members of the Ras GTPase superfamily that were initially recognized a
Phage－Titer
IntroductionLambda phage is a commonly used vector for transgenes. Its very high rate of infectivity makes it ideal for creating large numbers of clon
免疫荧光
Immunofluorescence Technique (Spector Lab)protocol for immunofluorescence on cells Immunofluorescence Protocol (Walter Steffen)Methanol fixationForma
Measurement－of－primary－endothelial－cell－permeability－to－fluxes－of－dextran..
Measurement of primary endothelial cell permeability to fluxes of dextran or albuminThe fluxes of albumin or dextran across vascular endothelial cell
Spectrophotometry
A spectrophotometer or colorimeter makes use of the transmission of light through a solution to determine the concentration of a solute within the sol
RNA－Electrophoresis
Electrophoresis through agarose or polyacrylamide gels is the standard way to separate, identify and purify nucleic acid fragments. The location of th
高通量ITS测序成鉴定真菌性角膜炎诊断补充方法
真菌性角膜炎是一种由致病真菌引起的高致盲性角膜炎。随着抗生素和糖皮质激素的广泛使用，其发病率不断增高。培养法一直被用作诊断真菌性角膜炎的金标准，但实际诊断效果并不尽如人意。 在真核生物的核糖体DNA中，ITS序列作为非编码区，其长度和序列在物种间的差异相对较大，因此可用于对不同真菌种属的分类
ITS公司展示小巧便携的科研仪器用于微纳尺度分析
2013年5月17日，由中国化学会主办、厦门大学承办、复旦大学、浙江大学协办的第八届全国微全分析系统学术会议、第三届全国微纳尺度生物分离分析学术会议暨第五届国际微化学与微系统学术会议在美丽的海滨城市厦门隆重召开，400余名国内外学者参加了这一盛会。1978年
Detection－and－Measurement－of－Radioactivity
Radioactive DecayIsotopes of a given element have nuclei with the same number of protons but different numbers of neutrons. Some isotopes are stable,
High－resolution－negative－staining
High resolution negative staining(From Valentine et al, 1968. Biochemistry 7:2143-52)Rationale: For the highest resolution with negative staining, the
流式细胞仪技术专辑
Flow Cytometry Analysis (Springer Lab, Harvard University) Flow cytometry employs instrumentation that scans single cells flowing past excitation sour
Basics－of－Electrochemical－Impedance－Spectroscopy（四）
We will calculate two examples to illustrate a point about combining circuit elements. Suppose we have a 1 Ω and a 4 Ω resistor in series. The i
Measurement－of－Carbon－Fixation－Rates－in－Leaf－Samples
Generation of a Light Curve To address the hypothesis concerning photosynthetic efficiency it is necessary to expose sun and shade leaves to a ran
Dendritic－cells－in－regulating－TH1－and－TH2－Development
While T cells and B cells carry out the actions of antigen-specific immune responses, antigen-presenting cells called dendritic cells are required for
Dynabeads®－Streptavidin－Trial－Kit（二）
3. General Immobilization Protocol Wash the Dynabeads® before use. a) Add the biotinylated molecule to the washed Dyn
Attenuation－of－GPCR－Signaling
The G-protein coupled receptor (GPCR) family transduces extracellular signals across the plasma membrane, activating cellular responses through a vari
Centrifugation2
RELATIVE CENTRIFUGAL FORCE Figure F.2. Nomogram for R.C.F.Modern day ultracentrifuges can generate forces in excess of 300,000 times that of gravity,
Gammaaminobutyric－Acid－Receptor－Life－Cycle
Gamma-amino butyric acid (GABA) is an inhibitory neurotransmitter that acts at synapses through binding to ligand-gated ion channels, the GABA recepto
Gamry电化学工作站：拉曼光谱电化学基础
Gamry电化学工作站：拉曼光谱电化学基础Purpose of This NoteThis application note discusses Raman spectroscopy and its combination with electrochemical techniques.The th