LectinInducedComplementPathway
The complement cascade of proteolytic factors involved in cellular lysis can be initiated by several different factors, including antibody-dependent and antibody-independent recognition of infectious organisms (see classical and alternative complement pathways). In the lectin-induced complement cascade, carbohydrates on the surface of microbial cells activate the complement cascade by binding to mannan-binding lectin......阅读全文
Trka－Receptor－Signaling－Pathway
Nerve growth factor (NGF) is a neurotrophic factor that stimulates neuronal survival and growth through TrkA, a member of the trk family of tyrosine k
IL－2－signaling－pathway
Interleukin 2 (IL-2) is a potent cytokine that can lead to cellular activation and proliferation. IL-2 Receptors are found on activated B-Cells, LPS t
简述P选择素的组成结构
P 选择素(granular membrane protein 140,GMP140 ), 血小板活化依赖性颗粒表面膜蛋白(platelet activation dependent granule external membrane protein ,PADGEM )或CD 62 p ,是一种
P选择素的组成结构
P 选择素的结构和特性 P 选择素(granular membrane protein 140,GMP140 ), 血小板活化依赖性颗粒表面膜蛋白(platelet activation dependent granule external membrane protein ,PADGEM )
Interleukin6－Induced－Acute－Phenotypic－Microenvironment－Promote...（十）
In this study, we found that “acute” response was strongly induced by cryo-thermal therapy with “acute” and high expression of a series of acute p
TNFR1－Signaling－Pathway
TNFR1 (a.k.a. p55, CD120a) is the receptor for TNF(alpha) and also will bind TNF(beta). Upon binding TNF(alpha) a TNFR1+ cell is triggered to undergo
The－salvage－pathway－from－serine－to－phosphatidylcholine
The biosynthesis of membrane phospholipids occurs through distinct pathways in mammals and bacteria. In the mammalian pathway for the synthesis of pho
Oxidative－reactions－of－the－pentose－phosphate－pathway
One form of chemical energy used to drive biosynthetic reactions forward is the reducing power of the energy carrier NADPH. NADPH is essential to driv
IGF1－Signaling－Pathway
Insulin like growth factor 1 (IGF-1) and its receptor (IGF-1R) provide a potent proliferative signaling system that stimulates growth in many differen
Chaperones－modulate－interferon－Signaling－Pathway
Signaling by interferon-gamma stimulates anti-viral responses and tumor suppression through the heterodimeric interferon-gamma receptor. Signaling is
T－Cell－Receptor－Signaling－Pathway
The T Cell Receptor plays a key role in the immune system. The specificity of the receptor is governed by the binding site formed from the mature alph
Phospholipase－Cepsilon－pathway
Proposed model for b2-AR- and prostanoid-receptor-mediated PLC and calcium signalling. Receptors coupling to Gs stimulate AC, resulting in elevated cA
Nerve－growth－factor－pathway－(NGF)
Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture NGF induces the f
p53－Signaling－Pathway
p53 is a transcription factor who's activity is regulated by phosphorylation. The function is p53 is to keep the cell from progressing through the
OX40－Signaling－Pathway
Two key features of the immune system are the clonal expansion of B cells and T cells in response to antigens, and the potentiation of future immune r
Platelet－Amyloid－Precursor－Protein－Pathway
The amyloid -beta peptide (Ab), a proteolytic fragment of amyloid precursor protein (APP), is the major componenet of senile plaques, the hallmark of
TNFR2－Signaling－Pathway
TNFR2 is the receptor for the 171 amino acid 19 kD TNF(beta) (a.k.a. lymphotoxin). TNF(beta) is produced by activated lymphocytes and can be cytotoxic
CXCR4－Signaling－Pathway
CXCR4 is a chemokine receptor in the GPCR gene family, and is expressed by cells in the immune system and the central nervous system. In response to b
NFkB－Signaling－Pathway
Nuclear factor kB (NF-kB) is a nuclear transcription factor that regulates expression of a large number of genes that are critical for the regulation
Rho－cell－motility－signaling－pathway
RhoA is a small G-protein in the Rho family that regulates cell morphology via actin cytoskeleton reorganization in response to extracellular signals.
ER–associated－degradation－(ERAD)－Pathway
The endoplasmic reticulum (ER) of the cell operates a quality control system that identifies misfolded proteins, transports them into the cytoplasm an
Stat3－Signaling－Pathway
STATs, Signal Transducers and Activators of Transcription, are transcription factors that are phosphorylated by JAK kinases in response to cytokine ac
TollLike－Receptor－Pathway
The innate immune response responds in a general manner to factors present in invading pathogens. Bacterial factors such as lipopolysaccharides (LPS,
Msp/Ron－Receptor－Signaling－Pathway
MSP, macrophage-stimulating protein, acts through the transmembrane receptor kinase RON (Stk in mice) to play a role in inflammation and the response
CBL－mediated－ligandinduced－downregulation－of－EGF－receptors
As with many cell-surface receptors, activation of the EGF receptor can result in receptor internalization through receptor-mediated endocytosis, dese
TSP1－Induced－Apoptosis－in－Microvascular－Endothelial－Cell
As tissues grow they require angiogenesis to occur if they are to be supplied with blood vessels and survive. Factors that inhibit angiogenesis might
RasIndependent－pathway－in－NK－cellmediated－cytotoxicity
NK (natural killer) cells are lymphocytes distinct from B and T cells that induce perforin-mediated lysis of tumor cells and virus-infected cells. NK
补体旁路的概念
中文名称补体旁路英文名称alternative complement pathway定 义不经C1、C4、C2活化,而是在B因子、D因子和P因子参与下,直接由C3b与激活物结合启动补体酶促连锁反应,产生一系列生物学效应和最终发生细胞溶解作用的补体活化途径。应用学科细胞生物学（一级学科），细胞免疫（
补体旁路的概念
中文名称补体旁路英文名称alternative complement pathway定 义不经C1、C4、C2活化,而是在B因子、D因子和P因子参与下,直接由C3b与激活物结合启动补体酶促连锁反应,产生一系列生物学效应和最终发生细胞溶解作用的补体活化途径。应用学科细胞生物学（一级学科），细胞免疫（
CD40L－Signaling－Pathway
The CD40 receptor was first associated with expression in B cells and the role it plays through its ligand CD40L (CD154) in moderating T cell activati