BiosynthesisofCysteineinmammals
In animals, the sulfur-containing amino acid cysteine is synthesized from homocysteine, which is itself derived from metabolism of the amino acid methionine. Methionine is an essential amino acid for animals, making cysteine indirectly an essential amino acid as well. Homocysteine condenses with serine to form cystathionine, which is deaminated and hydrolyzed to form cysteine and alpha-ketobutyrate. While the sulfur ......阅读全文
Biosynthesis－of－Cysteine－in－mammals
In animals, the sulfur-containing amino acid cysteine is synthesized from homocysteine, which is itself derived from metabolism of the amino acid meth
Biosynthesis－of－Cysteine－from－serine－in－bacteria－and－plants
In animals cysteine is synthesized from homocysteine, a produce of the essential amino acid methionine. In the absence of dietary methionine, animals
Biosynthesis－of－neurotransmitters
Neurotransmitters are signaling molecules used by neurons to communicate across chemical synapses. The receptors for neurotransmitters include G-prote
Biosynthesis－of－isoleucine
Isoleucine is an essential amino acid, only synthesized in plants and bacteria, and required in the diet by animals. In proteins, the hydrophobic isol
Biosynthesis－and－Analysis－of－Bilins
The term bilin is a collective one to describe a broad group of open chain tetrapyrroles and derives from the name “bile pigments” as the first o
Biosynthesis－of－threonine－and－methionine
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Phosphatidylcholine－Biosynthesis－Pathway
The main components of biological membranes are phosphoglyceride lipids composed of a glycerol unit esterified to two fatty acids and a polar alcohol
Biosynthesis－of－Glycine－and－Serine
Intermediates in energy production pathways such as glycolysis and the Kreb's cycle are commonly the starting point for the biosynthesis of amino
Biosynthesis－of－spermidine－and－spermine
The polyamines spermidine and spermine are expressed in a variety of tissues and are involved in the regulation of apoptosis, cellular proliferation,
Biosynthesis－of－Proline－in－Bacteria
Among the twenty amino acids encoded by the genetic code, proline is unique in having a cyclic structure with its side chain connected to the amino gr
Catabolic－pathways－for－alanine,－glycine,－serine,－cysteine,－tryptophan
Amino acids in the diet have one of two fates - either they are incorporated into proteins or they are broken down for energy and metabolic intermedia
Biosynthesis－of－Tryptophan－in－Bacteria－and－Plants
The aromatic amino acid tryptophan is an essential nutrient, meaning that humans and animals do not themselves have the biosynthetic machinery to synt
Biosynthesis－of－Chorismate－in－Bacteria－and－Plants
The biosynthesis of all three aromatic amino acids (tryptophan, tyrosine and phenylalanine) begins with the metabolic intermediate chorismate. The bio
Phospholipid－Biosynthesis－in－E.－Coli－Pathway
The biosynthesis of membrane phospholipids occurs through distinct pathways in mammals and bacteria. In the mammalian pathway for the synthesis of pho
The－salvage－pathway－from－serine－to－phosphatidylcholine
The biosynthesis of membrane phospholipids occurs through distinct pathways in mammals and bacteria. In the mammalian pathway for the synthesis of pho
欧盟发布茚虫威对哺乳动物和蜜蜂风险的最新同行审查
据欧盟食品安全局（EFSA）消息，2019年10月29日，欧盟食品安全局发布活性物质茚虫威（indoxacarb）对哺乳动物和蜜蜂的风险的最新同行审查。 经过评估，茚虫威对哺乳动物和蜜蜂的长期风险有关的关键问题仍然存在。 部分原文报道如下： Following the completion
专化性的麦角甾醇合成抑制剂
α-Bisabolol from Chamomile – A specific ergosterol biosynthesis inhibitor? SummaryThere is a strong need for new antifungal agents with a differen
FXR－and－LXR－Regulation－of－Cholesterol－Metabolism
Cholesterol is essential for life and a key in the development of heart disease. Cholesterol homeostasis is achieved through regulation of cholesterol
潜在抗癌新药LNM－E1开发者沈奔教授团队再次取得重大进展
斯克里普斯研究所（Scripps Research Institute，TSRI）佛罗里达校区的一支跨国科学家团队通过未知功能结构域（domain of unknown function，DUF）和半胱胺酸裂解酶结构域（cysteine lyase domain，SH）双结构域系统进化分析，在细
营养学词汇半胱氨酸基本信息
中文名称：半胱氨酸中文别名：L-半胱氨酸; L-2-氨基-3-巯基丙酸; (R)-2-氨基-3-巯基丙酸;英文名称：L-Cysteine英文别名：H-CYS-OH; H-Cys-OH; CYSH; FEMA 3263; Cystein;L-Cysteine; E 920; L-Cys; CYSTEI
L半胱氨酸的基本信息
中文名称：半胱氨酸中文别名：L-半胱氨酸; L-2-氨基-3-巯基丙酸; (R)-2-氨基-3-巯基丙酸;英文名称：L-Cysteine英文别名：H-CYS-OH; H-Cys-OH; CYSH; FEMA 3263; Cystein;L-Cysteine; E 920; L-Cys; CYSTEI
半胱氨酸的基本信息
中文名称：半胱氨酸中文别名：L-半胱氨酸; L-2-氨基-3-巯基丙酸; (R)-2-氨基-3-巯基丙酸;英文名称：L-Cysteine英文别名：H-CYS-OH; H-Cys-OH; CYSH; FEMA 3263; Cystein;L-Cysteine; E 920; L-Cys; CYSTEI
高分辨质谱仪实现非变性状态ADCs－药物的分析（一）
1 前言单克隆抗体被认为是具有高度特异性的靶向药物，其对肿瘤细胞的靶向性非常高。而抗体- 药物偶联物（Antibody-drug conjugates，以下简称ADCs）技术，就是在抗体蛋白的特定氨基酸上偶联具有抗肿瘤作用的高效应化疗药物（或称小分子药物），以增加单克隆抗体的疗效、并降低小分子药
Shuttle－for－transfer－of－acetyl－groups－from－mitochondria－to－the－cytosol
Acetyl-CoA is produced in mitochondria through the metabolism of fatty acids and the oxidation of pyruvate to acetyl-CoA. When ATP is needed, this ace